    ID   AF438419   standard; circular other DNA; PRO; 12959 BP.
    XX
    AC   AF438419;
    XX
    SV   AF438419.1
    XX
    DT   02-NOV-2002 (Rel. 73, Created)
    DT   05-SEP-2003 (Rel. 77, Last updated, Version 2)
    XX
    DE   Lactobacillus sakei plasmid pRV500, complete sequence.
    XX
    KW   .
    XX
    OS   Lactobacillus sakei
    OC   Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus.
    OG   Plasmid pRV500
    XX
    RN   [1]
    RP   1-12959
    RA   Alpert C.A., Crutz-Le Coq A.M., Malleret C., Zagorec M.;
    RT   "Characterization of a Theta-Type Plasmid from Lactobacillus sakei: a
    RT   Potential Basis for Low-Copy-Number Vectors in Lactobacilli";
    RL   Appl. Environ. Microbiol. 69(9):5574-5584(2003).
    XX
    RN   [2]
    RP   1-12959
    RA   Alpert C.A.;
    RT   ;
    RL   Submitted (23-OCT-2001) to the EMBL/GenBank/DDBJ databases.
    RL   Unite Flore Lactique et Environnement Carne, Institut National de la
    RL   Recherche Agronomique, Domaine de Vilvert, Jouy en Josas 78350, France
    XX
    DR   GOA; Q8GQB2.
    DR   GOA; Q8GQB3.
    DR   GOA; Q8GQB4.
    DR   GOA; Q8GQB5.
    DR   GOA; Q8GQB6.
    DR   GOA; Q8GQB7.
    DR   GOA; Q8GQB8.
    DR   GOA; Q8GQB9.
    DR   GOA; Q8GQC0.
    DR   GOA; Q8GQC1.
    DR   GOA; Q8GQC2.
    DR   GOA; Q8GQC3.
    DR   GOA; Q8GQC4.
    DR   SPTREMBL; Q8GQB2; Q8GQB2.
    DR   SPTREMBL; Q8GQB3; Q8GQB3.
    DR   SPTREMBL; Q8GQB4; Q8GQB4.
    DR   SPTREMBL; Q8GQB5; Q8GQB5.
    DR   SPTREMBL; Q8GQB6; Q8GQB6.
    DR   SPTREMBL; Q8GQB7; Q8GQB7.
    DR   SPTREMBL; Q8GQB8; Q8GQB8.
    DR   SPTREMBL; Q8GQB9; Q8GQB9.
    DR   SPTREMBL; Q8GQC0; Q8GQC0.
    DR   SPTREMBL; Q8GQC1; Q8GQC1.
    DR   SPTREMBL; Q8GQC2; Q8GQC2.
    DR   SPTREMBL; Q8GQC3; Q8GQC3.
    DR   SPTREMBL; Q8GQC4; Q8GQC4.
    XX
    FH   Key             Location/Qualifiers
    FH
    FT   source          1..12959
    FT                   /db_xref="taxon:1599"
    FT                   /mol_type="other DNA"
    FT                   /organism="Lactobacillus sakei"
    FT                   /plasmid="pRV500"
    FT   repeat_region   555..654
    FT   gene            721..1656
    FT                   /gene="repA"
    FT   CDS             721..1656
    FT                   /codon_start=1
    FT                   /db_xref="GOA:Q8GQC4"
    FT                   /db_xref="SPTREMBL:Q8GQC4"
    FT                   /evidence=EXPERIMENTAL
    FT                   /transl_table=11
    FT                   /gene="repA"
    FT                   /product="RepA"
    FT                   /protein_id="AAN61991.1"
    FT                   /translation="MGNEIIKYDPELNTIPLRKFTPVEMNLFFSIISRMRDKSNQTIRF
    FT                   TFDQLKELSAYKPTANNRFEDDIQRTYEKMMGLHFGRRSKSGLTREFFVLFTEFKIDGD
    FT                   AKEPYVDVKVYERALPLLNKLESWVRYALAEFRDLKSSYAKTMFRLLKQFRTTGYAYFS
    FT                   KEDFFELLDMPKSYWSSPSNVDKFVIKPIKEELTPLFRGLTVRKKYGKGRGKPVIGYTF
    FT                   TWKPEKKDANDFSQGKFQDERQKLFNIQNNGELTEQEKWRATDKVKGLPLGSTEKQILA
    FT                   ERQIEHDKKIRDQTRQEMLAELRKGFGKHA"
    FT   CDS             1782..2351
    FT                   /codon_start=1
    FT                   /db_xref="GOA:Q8GQC3"
    FT                   /db_xref="SPTREMBL:Q8GQC3"
    FT                   /transl_table=11
    FT                   /product="ORF-6"
    FT                   /protein_id="AAN61992.1"
    FT                   /translation="MSENLKTIRELADEFNVSKQAVRKRLTDEFRANYVETVHSNGVKT
    FT                   LVVTVTGYMLLKQHFSGGNSDVKVASNVGGNDGNLDVASDSKKNDDEVSVLKILEQQLA
    FT                   VKDQQLENKDLQISQMQNLLDQQQRLALQDKKMLEDYKAKIQNLEALAMTPHDSEKELS
    FT                   PKNKPEQETSTVERQHKTKKWWHFGR"
    FT   gene            2517..4049
    FT                   /gene="hsdM"
    FT   CDS             2517..4049
    FT                   /codon_start=1
    FT                   /db_xref="GOA:Q8GQC2"
    FT                   /db_xref="SPTREMBL:Q8GQC2"
    FT                   /evidence=NOT_EXPERIMENTAL
    FT                   /note="hypothetical"
    FT                   /transl_table=11
    FT                   /gene="hsdM"
    FT                   /product="HsdM"
    FT                   /protein_id="AAN61993.1"
    FT                   /translation="MAKKTAELKIEDALWQAADQLRGSMDASQYRNVVLGLIFLKYVSD
    FT                   SFNEKYESLIKSDYPEDAEDRDMYTAENIFWLPKEARWDVIASDAKTPEIGETIDKAME
    FT                   AIERENDQIKGVLPKNYASPDLDKVRLGGVIDLISNIKVGDEESRKNDVLGRVYDYFLS
    FT                   NFAAQEGKNGGEFYTPRSIVRTLVEMLEPYKGRIYDPAAGSGGMFVQSEEFVREHQGVI
    FT                   SDLSVYGQEANPTTWKLAKMNLAIRGIDNDFGPHQGDTFTNDLHKGRRFDYILANPPFN
    FT                   LKEWGADKLQDDSRWVYGVPPEGNANYAWIEHMISKLAPDGKAGFVLANGALSTSTKEE
    FT                   YAIRKAILEADKIDAIVALPGQMFYSTQIPVSLWFVDMNKASSDERKRNGETLFIDARE
    FT                   LGFMADRTHKEFAREDIAKIADTYHAYRGTNDQVYEDVPGFSKAAMIEEIRENDYVLTP
    FT                   GRYVGLAERQDDGEPYEEKMARLTSELSDQFKKSAELEEQIRDALKEIGYDI"
    FT   gene            4039..4494
    FT                   /gene="hsdS'"
    FT   CDS             4039..4494
    FT                   /codon_start=1
    FT                   /db_xref="GOA:Q8GQC1"
    FT                   /db_xref="SPTREMBL:Q8GQC1"
    FT                   /evidence=NOT_EXPERIMENTAL
    FT                   /note="hypothetical"
    FT                   /transl_table=11
    FT                   /gene="hsdS'"
    FT                   /product="HsdS'"
    FT                   /protein_id="AAN61994.1"
    FT                   /translation="MIFSDFIELHRGYDLPKAKRNADGLVPVIAAGGYDGFHDAAKVQG
    FT                   PGVITGRSGTLGSVYFNTTDFWPLNTTLFVSNFKGNDPLFVYYYLKTMDLGRYATGTTV
    FT                   PTLNRNHLDQIKVNIPDLAQQREIANKLNLFDEKISMLNDINDNLAA"
    FT   gene            complement(4491..5615)
    FT                   /gene="hsdS"
    FT   CDS             complement(4491..5615)
    FT                   /codon_start=1
    FT                   /db_xref="GOA:Q8GQC0"
    FT                   /db_xref="SPTREMBL:Q8GQC0"
    FT                   /evidence=NOT_EXPERIMENTAL
    FT                   /note="hypothetical"
    FT                   /transl_table=11
    FT                   /gene="hsdS"
    FT                   /product="HsdS"
    FT                   /protein_id="AAN61995.1"
    FT                   /translation="MTKVKLGDYVSLQTHKVDNLTAVNTSYVSTENLQPNRNGVLFPAA
    FT                   SVPSSGKVNFYDVGDILVSNIRPYFKKIWMAINPGTHSGDVLNFRTKSPKLTQEYLYIV
    FT                   LESDSFFDYVTLTSKGTKMPRGDKDAIMDFEFSLPSLDVQQKLSNTIMALERKILMSKQ
    FT                   VNDNLLELADATFKKNYEQQVGNQKLETLATVKGGKRLPKGAPLTEVKTQHPYLRITDY
    FT                   SKNGVPSVQSMQYITEEVFDKISRYVINEGEVFLSIVGTIGIVDLIDERLDNASLTENA
    FT                   VKIHAQTTAMAHYLYLYLRSDEGRHEIDSRTVGTTQKKLAITRIKDFDVGVISETDLQE
    FT                   FERTVSPLINMVLANRSEIDTLVQIRDSLLQELI"
    FT   CDS             complement(5612..6571)
    FT                   /codon_start=1
    FT                   /db_xref="GOA:Q8GQB9"
    FT                   /db_xref="SPTREMBL:Q8GQB9"
    FT                   /transl_table=11
    FT                   /product="ORF-2"
    FT                   /protein_id="AAN61996.1"
    FT                   /translation="MQAELLTQITALVGSQFADSISNILSNYDITRKTAPIPPTNTQLL
    FT                   NLFLSAKTIEGKSPKTMMYYKNTLTRLLTTTKKTIKQTTTNDLRNYLSEFQNTHGVSNV
    FT                   TIDNIRRILSSFFSWLEDEDFIIKSPMRRIHKVKTIKVVNKTLSDEDLEKIRETASSYR
    FT                   DRAIVEFLASTGVRVGEIVNLDINAIRLAERSAIVLGKGNSEREVYFDARTKIHLERYL
    FT                   KTRTDKNEALFVSHKRPNNRLTIGTIESIVKKIGEKSLVNHVHPHKFRRTLATRAIDKG
    FT                   MPIEQVQKLLGHVRIDTTMNYAMVNQTNVKISHRKYIG"
    FT   gene            6759..9923
    FT                   /gene="hsdR"
    FT   CDS             6759..9923
    FT                   /codon_start=1
    FT                   /db_xref="GOA:Q8GQB8"
    FT                   /db_xref="SPTREMBL:Q8GQB8"
    FT                   /evidence=NOT_EXPERIMENTAL
    FT                   /note="hypothetical"
    FT                   /transl_table=11
    FT                   /gene="hsdR"
    FT                   /product="HsdR"
    FT                   /protein_id="AAN61997.1"
    FT                   /translation="MSVSSFTLENDVEQQAIDWLVAQGYQDLRATSNGGRNEQIYLERG
    FT                   SDEHNILLTGRLRLAFERLNPGYTDDDYSEAVRQMQRLADSPDMMIDNHKMHKFLIEGV
    FT                   KIQRSVNGENRTLTLRPIDFKNVESNDFVVTNQVTVLQGDHNRRPDIVLYINGLPLVTF
    FT                   ELKNLSNVDAGISNAYNQFQTYKREISNFMRYNEILVTADMVQARAGSLTADESRFMQW
    FT                   RLPEEVNGSSKPLFQLESLIRGMMNPITLLNLIQNFIIFETDGDKTIKILAAYHQYYMV
    FT                   NKAVTSAKRTVETPGDNQIGVVWHTQGSGKSLSMVFFSGIVGRELGNPTIVVINDRNDL
    FT                   DNQLSGTFAAASEFLGQEPKQADSREDMRRLLSVNSGGIVFTTMQKFSPEFENGETDMP
    FT                   VLTARDNVIVMADEAHRTQYGLGAKYSKDGETKYGYAKYLRDALPNASYIGFTGTPIDM
    FT                   SDKSTKAVFGDYIDVYDMTRAVEDHATVKIYYESHVIPLDWDKAELTEEVIEFLDNDLD
    FT                   ENPDTAKYARLEALAGSAPRVKKLAEHFVEHFETRQKAEDGKSMIVAMSRRNAVAIYDA
    FT                   IVKLRPEWHSDDLDKGKIKIIFTANASDDEYLTKHHTNKKEREHLQRRMKNDADELKIV
    FT                   IVVDMWLTGFDAPSTNTMYIDKPMKGHNLMQAIARVNRVFKDKDSGLVVDYIGIADNLK
    FT                   SALQQYSPSDQEQAGINIEKAISVMQEKYNIITRDYLYGVDYSNFNSSDRSLKLETFRN
    FT                   VLNDLLSPEEFSVNATPYNNAEPIDPDKLTERQTAFRDTVTQLQRAFALVATTSEAQTI
    FT                   SEELAFFVALKNAMIKMIVTSEGGVEKSIDYRMRQLLDRSIIPGEVVDLYKDLGLNRPE
    FT                   LDLLSDEFLDEVQNMPQKNVALDLLERLLKGQVKALTCTNLVKAKKFDEMLAASIELYN
    FT                   ARGLTTEIVIRQLIDIAKDINKAQKEGEKLGLSPEEVAFYDALADHDKAREEMGEEKLH
    FT                   QLAAKLVEEVRKNTGTDWVRRDSTRAQMRVAVKKLLRQFGYPPDFAAEAIDTVVTQAEK
    FT                   MALNES"
    FT   CDS             complement(10211..10999)
    FT                   /codon_start=1
    FT                   /db_xref="GOA:Q8GQB7"
    FT                   /db_xref="SPTREMBL:Q8GQB7"
    FT                   /transl_table=11
    FT                   /product="ORF-13"
    FT                   /protein_id="AAN61998.1"
    FT                   /translation="MDSGKQSLNNNKMLEAITNNDFRSLLKLVVENPIAHVNRSEYLAK
    FT                   VFKVTESDIINGDLDISLKERKKVAQKQITATVRNTTVISFLTGIPGGIAIAGTIPGDI
    FT                   IQNMVYSIRLAQQLAYIYDFDDLIEEDGKIQTNGLLLFLGTMAGVNGSASLLRVSSSNA
    FT                   IKYASKQILGKPLMKTLWYPLLKKITSIVAGKTLTKKGLASGIAKIVPVVGGVTSGSIT
    FT                   MIGMEMSAKKLNSELLRGFEQNYSERDYEKDIKIIEAEII"
    FT   CDS             complement(11033..11317)
    FT                   /codon_start=1
    FT                   /db_xref="GOA:Q8GQB6"
    FT                   /db_xref="SPTREMBL:Q8GQB6"
    FT                   /transl_table=11
    FT                   /product="ORF-12"
    FT                   /protein_id="AAN61999.1"
    FT                   /translation="MSKIDAYVTERSKNNPDFAKLVEQENINLEVAVKVRDLRENMGMS
    FT                   QRAFASLIGKPQSTIARIENGSMNASTRVLSEIAQATNQRLTIQFMPVI"
    FT   CDS             complement(11314..11664)
    FT                   /codon_start=1
    FT                   /db_xref="GOA:Q8GQB5"
    FT                   /db_xref="SPTREMBL:Q8GQB5"
    FT                   /transl_table=11
    FT                   /product="ORF-11"
    FT                   /protein_id="AAN62000.1"
    FT                   /translation="MKKMEFDYYDWNEFKQFLDQLPDKDAAKLIATIQNIENNGLIIAE
    FT                   RQLWVKKLENNLYEIRSKRASNIQRAIYFQVQGSQYLITNAFTKKTQKTPESEKKIARN
    FT                   RRSKYFNKEDQQ"
    FT   CDS             11803..12390
    FT                   /codon_start=1
    FT                   /db_xref="GOA:Q8GQB4"
    FT                   /db_xref="SPTREMBL:Q8GQB4"
    FT                   /transl_table=11
    FT                   /product="ORF-10"
    FT                   /protein_id="AAN62001.1"
    FT                   /translation="MHQIVLPIKDSNVLNDVQDTLLNNFKAGRRNYTVFQVGKATLLRV
    FT                   SDVMRLKQTDIFNPDGSIKQNTFIHDRKTGKPNTLYLKPVQTELLLYRQWLLNHQLDSE
    FT                   WLFPSIQHPERHITEKQFYKIMSKVGDLLSINYLGTHTMRKTGAYRVYTQSNYNIGLVM
    FT                   HLLNHSSEAMTLAYLGLDQASTESMLDQIDFG"
    FT   CDS             complement(12287..12487)
    FT                   /codon_start=1
    FT                   /db_xref="GOA:Q8GQB3"
    FT                   /db_xref="SPTREMBL:Q8GQB3"
    FT                   /transl_table=11
    FT                   /product="ORF-9"
    FT                   /protein_id="AAN62002.1"
    FT                   /translation="MRTYTPQLKLLVFVLNFLYQKSPSATTKNPNKTNQNQFDLTYFRY
    FT                   WLGLSLNKLKSWLHLNDLISA"
    FT   CDS             12747..12959
    FT                   /codon_start=1
    FT                   /db_xref="GOA:Q8GQB2"
    FT                   /db_xref="SPTREMBL:Q8GQB2"
    FT                   /transl_table=11
    FT                   /product="ORF-8"
    FT                   /protein_id="AAN62003.1"
    FT                   /translation="MLGVIKIDEKKVLKPINEMLADPGQVDIQELFEASVNEPDEIKKN
    FT                   LYDSLYTYILQKRQEDIINRPGFVI"
    XX
    SQ   Sequence 12959 BP; 3992 A; 2236 C; 2696 G; 4035 T; 0 other;
         ccctctaaga gcctgctgag agctttttgt tttgctttgg tataaatgta tatgaatagt        60
         cttaaaattg ctagaaacga aaaataaggc cctaaaaaac gaacatagca gttaaatctt       120
         tatcaagttt tagaaaagct aactatttgc tgtcaatggt agcggacgag cgtagcgtgg       180
         gagcataagg aattgacagc tctaaaccag tcttaacact gaattggcga aagccaaagt       240
         ttctataaaa ctttgctttc ctgcctaacg gcgagtgaaa aagcggttaa gctggctcag       300
         cttggacggg gttcggggcg ttagcgcccg taataaatgt ggcttgccac acctttttag       360
         gaaacgaaca aagtgaggcg caaagagcgt agcgaatgga gtttaatgtg agccggtttt       420
         tggctcactc ctttgtgttt ttattttagg ttttgatctc gtacagtggt gcctcttata       480
         tacctctttt ataaacctct tttaaacctc ttttagaccc ctcttgaacc ttactccccc       540
         aagacttaca gaactttatc aagtaggttt tgtctgttta tcaagtaggt tttgtctgtt       600
         tatcaagtag gttttgtctg tttatcgagt aggttttgtc tgtttatcaa gtagtattat       660
         aaagttgact acttgataaa attaacttat attaaatttg taatgattag gaggtgcagc       720
         atgggaaacg aaattattaa atatgatcca gagttgaata ctattccact tcgaaaattt       780
         actccggttg aaatgaattt atttttttca attatttctc gtatgcgtga taagagtaat       840
         cagaccattc gctttacttt tgatcaatta aaagaattaa gtgcttataa accaactgca       900
         aataaccgtt ttgaagatga tattcagaga acttatgaaa aaatgatggg attacatttt       960
         ggtaggcgaa gtaaaagtgg attaactcga gagttttttg tcttgtttac agagtttaaa      1020
         atcgatggag atgcaaagga accttatgta gacgtaaaag tttatgaacg tgctttaccc      1080
         cttttaaaca agcttgaaag ttgggttcgt tatgctctag cagagttcag agatttgaag      1140
         agtagttacg caaaaactat gtttcgatta ctaaaacagt tccgaaccac tggatatgct      1200
         tatttttcta aagaagattt ttttgaatta ctcgatatgc ctaaaagtta ctggagtagt      1260
         ccatctaacg ttgataaatt tgttataaaa cccattaaag aagaattaac tcccttattt      1320
         agagggttaa cggttaggaa aaaatatggt aaaggtcgtg gaaaaccagt gattggttat      1380
         acctttactt ggaaacctga aaagaaagac gcaaacgact tttcccaagg taagttccaa      1440
         gacgagcgtc aaaaactttt taatatccag aataatggtg aattaacaga acaagaaaaa      1500
         tggcgcgcta ccgataaagt taaaggccta ccactaggct caactgaaaa acagatttta      1560
         gccgaacgac agattgagca tgataaaaaa ataagagatc agacaagaca agaaatgctt      1620
         gctgaactcc gaaaggggtt tggaaaacat gcctaaaact attagagaac ttgctgatga      1680
         attgaatgtc tccaaacaga ctattcaaaa ggacatcgct aagtgcctta aaaaatcgat      1740
         tgaacagtac ctaccaatag ttaaaaggca ggatatagag catgagtgaa aatttaaaaa      1800
         cgattcgaga acttgctgac gaatttaatg tatctaaaca agcagttaga aaaagattga      1860
         ctgatgaatt tagagcaaac tatgtagaaa ctgtacatag taacggggtg aaaaccttgg      1920
         tggtaacagt tactggttat atgcttttaa agcagcattt ttcaggtggt aattctgatg      1980
         ttaaagttgc tagtaacgtt ggtggcaacg atggtaattt agacgttgcc agtgatagta      2040
         agaaaaacga tgacgaagta tctgtactaa aaatattaga acaacaatta gctgttaaag      2100
         atcagcaact agaaaataaa gatttacaaa tatctcaaat gcaaaatcta ttagatcagc      2160
         aacaacggtt agccttacaa gacaaaaaaa tgctagagga ttacaaagca aaaatccaga      2220
         atttggaagc tttagcgatg acgcctcatg atagtgagaa agagttgtca ccgaaaaaca      2280
         aacccgaaca ggaaactagc actgtggagc gccaacataa aacaaaaaaa tggtggcatt      2340
         ttggtagata gagccaacaa aaaaagaaaa aagttagtta aatggctgaa tataaatttg      2400
         aacaccttta aatgtcttta tacgccgaag gtgcgactgg ttttatattt gtgtatgaat      2460
         atatttgttc agtacgtaaa atgaaataaa caacaatgaa tggtagagga ataggaatgg      2520
         ctaagaaaac ggcagaacta aaaattgaag atgctttgtg gcaagcggct gaccaattgc      2580
         gtggaagtat ggatgcttcc caatatcgta acgtggtttt gggattaatt tttttgaagt      2640
         acgtatctga ttcttttaat gaaaagtacg aatcattgat caagtcagat taccctgaag      2700
         acgcggaaga tcgtgatatg tatacggctg aaaatatctt ttggctacca aaagaagcac      2760
         gttgggatgt gattgcttcg gacgcaaaga cacctgaaat tggtgagact atcgataaag      2820
         caatggaagc aatagagcga gaaaacgatc aaataaaggg tgtgctgcca aagaattacg      2880
         catcaccaga tctggataag gttcgtcttg gtggagttat tgatcttatt tcgaatatca      2940
         aagttggtga tgaagagtcg cgaaagaatg atgtgttggg ccgcgtgtat gattactttt      3000
         tgagcaattt cgctgcacaa gaaggtaaga atggtggaga attctatacg cctcgttcaa      3060
         tcgtccgtac acttgttgag atgctggagc cgtacaaggg acgcatttat gaccctgcgg      3120
         ctggttctgg tggaatgttc gttcaatcgg aagaatttgt tcgtgagcac caaggtgtta      3180
         tttcagattt atcagtgtat ggtcaagaag ctaacccaac tacttggaaa ttggcaaaga      3240
         tgaatttggc gattcgtgga attgataatg actttggacc tcatcaaggg gatacgttca      3300
         caaatgattt gcacaaggga agacgttttg actacattct tgctaacccg cctttcaatt      3360
         tgaaggagtg gggggcagat aagcttcaag acgactcccg ttgggtttat ggcgttccgc      3420
         ctgaaggaaa tgccaattac gcttggattg aacacatgat tagcaagttg gcgcctgatg      3480
         gtaaggccgg gtttgtgttg gcaaatggtg cgctttcaac aagcacaaag gaagagtatg      3540
         caattcgaaa ggcgattctc gaggctgata agattgatgc gattgtcgcc ttgccaggtc      3600
         aaatgtttta ttcaacgcag attccagtct ctctttggtt tgttgatatg aataaagctt      3660
         cgagcgatga acgcaagcgc aacggcgaga ctttatttat tgatgcacgt gagttaggat      3720
         ttatggcaga tcgaacgcat aaggaattcg cacgggaaga tattgctaag attgcagata      3780
         cttaccatgc ctaccgtggg actaatgacc aggtctatga agatgtacca ggctttagta      3840
         aagcggctat gattgaagag attcgtgaga atgactacgt tttgacacct ggtcgttatg      3900
         taggtcttgc tgaacggcaa gacgatggtg aaccgtacga agagaagatg gctcgactaa      3960
         catctgaact ttcagaccaa ttcaaaaaga gcgccgaact ggaagaacaa attcgtgacg      4020
         ctctaaagga gattggttat gatatttagt gactttattg agttgcaccg tggatatgac      4080
         ttaccaaagg caaaacgaaa cgcagacgga ttagtacctg ttattgctgc gggaggatat      4140
         gacggatttc atgatgccgc caaggttcaa ggtcctgggg taataactgg acgatcaggt      4200
         acgttaggga gcgtttattt taacaccacg gatttttggc cattaaatac cacgttgttt      4260
         gtgtcaaatt ttaaagggaa cgatccgcta tttgtttatt actacctgaa aacaatggat      4320
         ttaggacggt atgcgacggg tacgacagta cctacgttga atagaaacca tttagatcaa      4380
         attaaggtaa atattccaga tttagctcaa caacgggaaa ttgccaataa gttgaattta      4440
         tttgacgaaa agataagtat gttgaacgac ataaatgata atttagcagc ttaaattaac      4500
         tcctgtagaa gcgagtctct aatttgtacc aaggtatcga tttcgctacg attggctaaa      4560
         accatattaa tcagtggact gacagttcgt tcgaactctt gtaaatccgt ctcagaaatc      4620
         acaccaacgt cgaaatcttt gattcgtgtg atagccagct tcttttgagt agtgcccact      4680
         gtacgtgagt ctatctcatg acgcccttca tcggatctta aatagagata aagatagtgt      4740
         gccatagccg tcgtttgagc atgaatcttt accgcattct cagttaaaga agcattgtcc      4800
         agccgttcat cgattaagtc aacaattcca atagttccga ctattgataa gaacacctca      4860
         ccctcattaa tgacataacg actgatttta tcaaacactt cttccgtgat gtattgcatt      4920
         gattgtacgg atggtacgcc attctttgaa taatctgtaa ttctcaaata ggggtgctgt      4980
         gtttttactt cggtaagggg cgcccccttt ggtagccgct ttccgccctt gactgtcgca      5040
         agggtttcta gtttttggtt accaacttgc tgctcataat ttttcttgaa tgtagcatca      5100
         gccaattcga gtaaattatc atttacttgt ttagacatta aaatttttct ctccaatgcc      5160
         atgatggtgt tggagagttt ttgttgtaca tcaagactgg gcaaagaaaa ctcaaagtcc      5220
         atgatggcat ccttgtcacc ccgaggcatt tttgtgcctt ttgaagttaa tgtaacgtag      5280
         tcaaaaaaag agtcgctctc aagaacaata tatagatact cttgagtaag cttgggggac      5340
         ttggtgcgaa aattcagaac atcaccggag tgtgtaccag ggttaatggc catccaaatt      5400
         tttttgaagt atggacgaat atttgaaaca agaatatctc cgacgtcata gaaattcacc      5460
         tttcctgaag agggcacgga agccgctggg aacagtaccc cgtttctgtt tggttgaagg      5520
         ttttctgttg aaacgtaact cgtattaacg gctgtaaggt tgtcaacttt gtgtgtttga      5580
         agtgagacat agtcacctaa ttttactttt gtcatccaat atacttccta tgagatattt      5640
         ttacgttagt ttggtttacc attgcgtagt tcattgtagt atcaattcgt acgtgtccca      5700
         gtaacttttg tacttgttca atgggcatac ctttatcgat tgctctagta gccaacgtgc      5760
         gcctgaattt gtgtgggtga acatggttaa ccaatgattt ttcaccaatc tttttaacga      5820
         ttgattctat tgtaccaatg gttagacgat tgtttggcct tttgtgtgaa acaaacaatg      5880
         cctcgttctt gtcggttcta gtttttagat aacgttctag gtgaattttg gttctagcgt      5940
         caaagtaaac ttcacgctca ctattcccct ttccaagaac aatggcagaa cgttcagcta      6000
         gtctaatcgc gttgatatca aggttaacaa tttctccaac acgaacccca gttgatgcca      6060
         gaaactcaac aatggcacga tccctataag atgaagccgt ctcgcgaatc ttttcaagat      6120
         cttcatcaga taaagttttg ttaacaacct tgattgtctt taccttgtga atacgacgca      6180
         ttggggattt tatgatgaaa tcctcgtcct ccagccaaga aaaaaagctg gataaaatac      6240
         gacggatgtt atcaatagtg acgttgctta ccccatgtgt attctgaaat tctgatagat      6300
         aatttctaag atcatttgta gtggtttgct ttatggtctt tttagtagtg gttaacaatc      6360
         gagtcagggt gtttttgtag tacatcatgg tctttggtga tttaccctca atcgtcttag      6420
         cagaaagaaa taagtttagg agttgggtat ttgttggagg gataggtgct gttttgcgag      6480
         tgatgtcata gttactaaga atattagata tagaatctgc aaattgtgat ccaacgagtg      6540
         ccgtgatttg ggttaatagt tctgcttgca taattcactc ctgaaataat atatttggag      6600
         tgagattata acaatcaatg gtgtttaaag taaatggtac ctcaagtaac ttatcatcta      6660
         cacatatacc attattacaa cagtataatg catacaaaaa tgaatctttt catattgggg      6720
         tacaatgtga tacataggtt atagggaagg taattactat gagtgtaagt tcgtttactt      6780
         tagaaaacga tgttgagcaa caagccattg attggttagt tgctcaaggt tatcaagatc      6840
         tgcgtgctac cagtaatggc ggacgtaatg aacagattta tttagagcgt ggaagtgatg      6900
         aacacaacat tttgttgacc ggtcgtttac gtttggcttt tgaacgcttg aatccaggat      6960
         atacggatga cgattatagt gaggctgtgc gccagatgca gcgtcttgca gatagccctg      7020
         acatgatgat tgataatcat aagatgcaca agttcttaat tgaaggcgtt aagattcaac      7080
         gttctgttaa tggtgaaaat cgaacattga ctttgcgacc aatcgatttc aagaacgttg      7140
         aatctaatga ttttgtagtg acaaaccagg ttactgtttt gcaaggggat cacaaccgtc      7200
         gtccggatat tgtgttatat atcaatggac taccgttggt gacgtttgaa cttaagaacc      7260
         tgtcgaatgt agatgcaggt atttcaaatg cttacaacca gttccagacg tacaaacgtg      7320
         aaatttccaa tttcatgcgt tataacgaaa tattggttac tgctgatatg gttcaggcac      7380
         gagctggttc tctaacagct gatgagtcga gattcatgca atggcggtta cctgaggaag      7440
         tgaacggtag ttctaaaccg ctatttcagc tagaaagcct tattcgagga atgatgaacc      7500
         caataacttt gttgaatttg attcagaact ttatcatatt tgaaacagat ggcgataaga      7560
         caatcaagat tcttgccgcg tatcatcagt actatatggt taacaaggca gtgacatctg      7620
         ctaagcgtac tgttgagacc ccgggtgaca atcaaattgg tgttgtttgg cacacgcaag      7680
         gatcgggaaa atcgttgtcg atggtctttt tctctggaat tgtcggtcgt gaactcggca      7740
         atcccacgat agttgtcatc aatgatcgta acgatttgga taatcaactg tcaggcacgt      7800
         tcgcagctgc aagtgaattc ttgggtcagg agcctaagca ggccgattca cgtgaagaca      7860
         tgcgtcgtct attgagtgta aattctggtg gtattgtgtt cacgaccatg caaaaattct      7920
         cacctgagtt tgaaaatggc gagaccgaca tgccagtttt aacagcccgt gacaatgtga      7980
         ttgtgatggc cgatgaggca catcgaacac agtacggctt aggggcaaag tattctaagg      8040
         atggtgaaac taagtatggt tacgctaagt accttcgcga tgctttgcca aacgcctcgt      8100
         acattggttt tactggtacg ccaatcgata tgtctgataa gtctactaag gccgtatttg      8160
         gtgattatat tgatgtttat gatatgaccc gagcggtaga agaccatgca acagttaaaa      8220
         tttattatga aagtcacgtt atcccactag attgggataa agcggaattg accgaagaag      8280
         tcatcgagtt cctggataat gatttagatg aaaatccaga tacggcaaag tatgcacgcc      8340
         ttgaagcact agctggatct gcacctcgag tgaagaagtt agctgaacat tttgtagaac      8400
         actttgagac acgtcaaaag gctgaagatg gtaaaagtat gattgtagct atgtcccgtc      8460
         gaaacgcagt tgctatctac gatgccattg tgaaactgcg tccggagtgg cattctgatg      8520
         atttggataa gggtaagata aaaattatat ttacagctaa tgcctctgat gatgagtatc      8580
         taacgaagca ccacacgaac aagaaggaac gtgaacactt gcaacgtcgt atgaagaatg      8640
         atgctgacga gttgaaaatt gttattgttg ttgatatgtg gctgacagga tttgatgcgc      8700
         cttcaactaa tactatgtac atcgacaagc caatgaaagg acacaatttg atgcaggcaa      8760
         tcgcccgcgt taatcgtgtt tttaaggaca aagattcagg cctagttgtg gattatattg      8820
         ggatcgctga caatttgaaa tcagcgttac aacagtattc accatccgac caagagcaag      8880
         ctgggattaa catcgaaaag gctattagtg tgatgcaaga aaaatataac atcattacac      8940
         gtgattattt atatggcgtt gattattcaa actttaattc cagtgatcgt tctttgaaac      9000
         ttgaaacatt tcgaaatgtg ctgaacgatt tactttcacc agaagaattt tctgtaaacg      9060
         caactccata taacaatgct gaacctattg atccagacaa gttaactgaa cgtcaaaccg      9120
         cattccgtga tacagtaacg caattacaac gtgcgtttgc tctagtcgct acgacatctg      9180
         aagctcagac tatttctgaa gaattagcct tctttgttgc attgaagaat gccatgatta      9240
         aaatgattgt cactagtgaa ggcggtgtcg agaagtctat tgactatcgt atgcgtcagc      9300
         tgctagatag gtctattatt cctggtgaag ttgttgattt atacaaggat ctgggattga      9360
         atcgtccaga actagacttg ctgtctgatg agttcttgga cgaagttcag aatatgccgc      9420
         aaaagaatgt ggcattggac ttgttggaac gattactaaa gggacaagtt aaagcattga      9480
         cttgtacaaa tttagttaaa gctaagaagt ttgatgagat gttggcagct tcaattgagt      9540
         tgtacaacgc ccgtggattg actaccgaaa ttgtgattcg acaattaatt gacatagcta      9600
         aggatattaa taaggcgcag aaggaaggtg aaaaactcgg cttgtcacct gaagaagttg      9660
         ctttttatga tgcattagcc gatcacgata aggctcgtga agaaatgggt gaagaaaagt      9720
         tgcatcaatt ggcagccaag ttggtcgaag aagtgcgtaa gaatactgga actgattggg      9780
         tacgacgtga ttcaacacgt gcgcaaatgc gggtggctgt taagaaactg ctacgtcaat      9840
         ttggatatcc gcctgatttt gcagcagaag cgattgatac tgttgtgaca caggcagaaa      9900
         agatggcctt aaacgagtcg tgaacaggcg aaaagtccag atggatttta taataaaatt      9960
         ccgaaatttc ttctcattgg gtaaaatatc ataataattt actttcattc gctactttta     10020
         tacctaataa cagtaaacat ttacaagtcc tcctggggtc cataaaagtt gttataagat     10080
         tttatagggt ctatattata aaaataaccc ctcaaaaaca ttgaaagaat agcccccaat     10140
         atctataatg tagatattgg gggttattta tatgtttata caatttatag tcccttgata     10200
         aggaccctat ttatattatt tctgcttcaa taatttttat atctttttca taatctcttt     10260
         ctgaataatt ctgttcaaat ccccttaata actctgaatt tagtttctta gctgacattt     10320
         ccattccaat catagttata cttcccgaag taaccccacc aacgactgga acaattttcg     10380
         caattccaga ggctagtccc tttttggtta gtgttttgcc agcaactata ctagttattt     10440
         tttttaataa tgggtaccac aaagttttca ttaaaggttt ccctaatatt tgtttagaag     10500
         catactttat agcattagaa cttgacaccc gcaacaaaga agctgatcca tttactccag     10560
         ccattgttcc taaaaataat aacaatccat ttgtttgaat ttttccatct tcttcgatca     10620
         aatcatcaaa atcatatata taggctaatt gttgagccaa tctgatggag taaaccatgt     10680
         tttgaataat atcgccaggt attgtccctg ctattgcaat tcccccggga attccagtaa     10740
         gaaaagaaat aacagtagta tttcttaccg ttgctgtaat ttgtttttgt gcaacttttt     10800
         ttctttcttt taaggaaata tctaagtccc cattgataat atctgattct gttactttaa     10860
         atacttttgc taaatattca gatctgttaa catgtgcaat tggattttca acgactaatt     10920
         ttaagagtga gcgaaaatca ttattggtga ttgcttctaa cattttatta ttatttaatg     10980
         attgcttacc tgaatccatt atttctagct ccttagcatt ggtagttttt aattatatta     11040
         ccggcataaa ttgaatggtt aatcgctgat tagttgcctg agcaatctca gataataccc     11100
         tagtcgaagc attcatcgat ccattttcaa tcctagcaat ggttgattgt ggtttaccaa     11160
         ttagactagc aaatgcacgt tgactcatac ccatattttc acggagatca cggactttaa     11220
         ctgctacctc taaattgatg ttttcttgtt caacgagttt tgcaaaatca ggattgtttt     11280
         tacttctttc agtaacatat gcgtcaattt tactcattgt tggtcctcct tgttaaaata     11340
         cttgctgcgt cgattccgag caattttctt ttcactttct ggtgtttttt gcgttttctt     11400
         tgtgaatgca ttggtgatta agtactgaga tccttgtact tggaaataga tagctctctg     11460
         aatatttgaa gctctcttag aacgaatctc atagagattg ttttctagct ttttgaccca     11520
         taattgacgt tctgcgatga ttagaccgtt attttcaata ttttgaatgg tcgcaattaa     11580
         tttggcagcg tctttatcag gtaattgatc caaaaattgt ttaaattcat tccagtcata     11640
         atagtcaaat tccatttttt tcatattcac atgatagctt attggctatc aaaaagcaaa     11700
         caaatatgtt attacacaaa tccttggtac aagcggaagt gtgaaattca tatttccgct     11760
         tgtaccaagg gattacgtct ccaccaacga ggtgattttt atatgcatca aattgtccta     11820
         ccaatcaaag attcgaatgt acttaatgat gttcaagata ctttactcaa taactttaaa     11880
         gctggccggc gtaactatac agtttttcaa gttggcaagg cgacactatt gcgagtcagt     11940
         gatgtcatgc gcttgaaaca gaccgatatt tttaatccgg acggttctat taaacaaaat     12000
         acgttcattc acgatcgaaa aacaggtaaa cctaatacct tgtacctcaa accagttcaa     12060
         acagagctct tattgtatcg ccaatggcta cttaatcatc agctagattc tgaatggctc     12120
         tttccgtcca ttcaacaccc agaacggcat attacggaaa aacagttcta taaaatcatg     12180
         agcaaagtcg gcgatctttt aagcattaat taccttggta cccacactat gcgcaaaact     12240
         ggggcttatc gcgtttatac gcaatccaat tacaatattg gcttagtcat gcacttatta     12300
         aatcattcaa gtgaagccat gactttagct tatttaggct tagaccaagc cagtaccgaa     12360
         agtatgttag atcaaattga ttttggttag ttttatttgg atttttagtt gttgccgaag     12420
         gcgacttctg atacaggaaa tttagcacaa acaccagcaa ttttaattgt ggtgtgtaag     12480
         tgcgcattga cctcgtttca ctcggtctgt tgataaccat aaaatcaatt tctgctattg     12540
         ttgaattgac tatattttta attcaattta tgtttgcacc taactaagat tgttatgttt     12600
         taaatattta aaaagtgttg cagattacgc tgttttaagc caaaattttt taattgcttt     12660
         gtgcagagaa tttttataag tttggtaaca aattttgaat aacggtgttg taagatctat     12720
         aaatctaaac tgaaatcatt attttgatgt taggagtcat taagattgac gaaaagaaag     12780
         tattaaaacc aattaatgaa atgcttgctg atcctgggca agttgatatt caagaattgt     12840
         ttgaagcttc tgtcaatgaa cctgacgaga ttaaaaagaa tttgtatgat tccttataca     12900
         cttatatttt gcaaaaaaga caagaagata ttattaatcg tcctggcttc gttatttag      12959
    //